• Results from the present study

  2019-06-28

  

  Results from the present study also showed improvement in timelines for measles immunisation, which is scheduled at 9 months of age, almost a gap of 6 months from the last vaccine according to EPI schedule for LMICs. Although the major focus up until now has been on reminder messages, the impact of

• Previous health emergencies have shown that it

  2019-06-28

  

  Previous health emergencies have shown that it can take time to organise global collective action and provide financing to the national and local level. In such situations, a global mechanism should offer a rapid injection of liquidity to affected countries. The World Bank\'s Pandemic Emergency Fina

• br CaMKII and heart failure progression CaMKII is a

  2019-06-28

  

  CaMKII and heart failure progression CaMKII is a multifunctional serine–threonine kinase, phosphorylating target proteins. Under resting conditions, CaMKII is inactive. A rise in intracellular Ca2+ stimulates binding of Ca2+ to calmodulin (CaM), a ubiquitous Ca2+-binding protein. The Ca2+/CaM com

• br Introduction Once metastatic breast cancer cells

  2019-06-28

  

  Introduction Once metastatic breast cancer Netilmicin Sulfate structure are in the bone marrow, they hijack signals coming from the normal bone remodelling process and promote bone degradation [1]. Bone degradation is caused by osteoclasts, which have the unique property to dissolve bone mineral

• br Conclusions br Source of funding br Conflict of interest

  2019-06-28

  

  Conclusions Source of funding Conflict of interest Acknowledgments Introduction Atrial fibrillation (AF) is an arrhythmia that is commonly seen and occurs more often in the elderly. In Japan, the overall prevalence of all types of AF based on the data from periodic health examinations

• TEE guidance can also be

  2019-06-28

  

  TEE guidance can also be helpful during pulmonary vein cryoablation for AF. Kerut et al. [9] described their first 20 cases of cryoablation for AF using TEE and found TEE to have better overall procedural imaging and monitoring for pericardial effusion or thrombus formation. They found TEE monitorin

• With the publication of this month s issue we

  2019-06-28

  

  With the publication of this month\'s issue, we mark \'s first birthday. I hope you will allow me to effuse for a moment in the manner of a new parent discovering the fascination of her offspring\'s everyday achievements… Since its conception in March, 2013, the infant has maintained a healthy int

• The effects of zoledronic acid are most likely due

  2019-06-27

  

  The effects of zoledronic UNC 0646 of are most likely due to impairment of the tumour-driven alterations to the bone microenvironment. This may render the bone marrow cavity unfavourable for metastatic growth, potentially redirecting tumour cells to other sites, including the periosteal surface. Wh

• For many decades scientists have

  2019-06-27

  

  For many decades, scientists have warned that human activity is pushing life on our planet beyond the point of no return. In the Earth\'s history there have been five mass extinction events, most recently the Cretaceous–Tertiary mass extinction that occurred almost 65 million years ago and was thoug

• br Materials and methods br Results

  2019-06-27

  

  Materials and methods Results Discussion The treatment regimen used in this study is generally safe and well tolerated. The process of generating therapeutic numbers of CART-138 Lamivudine molecular by limiting their dilutions proved to be quite difficult; however, the target cell dose was

• br Diagnostic criteria Brugada syndrome is definitively diag

  2019-06-27

  

  Diagnostic criteria Brugada syndrome is definitively diagnosed when a type-1 ST-segment elevation is observed in at least 1 right precordial lead (V1 and V2) [23], placed in a standard or a superior position (up to the second intercostal space) (Fig. 1C) [24,25], in the presence or absence of a s

• The results of our initial cross sectional analyses assessin

  2019-06-27

  

  The results of our initial cross-sectional analyses assessing the clinical characteristics of the patients participating in ASSAF-K are shown in Table 1. As compared with the “Fushimi AF Registry,” considered a representative Japanese AF registry with an initial registration of 3183 patients [28], t

• We propose that the same geospatial statistical

  2019-06-27

  

  We propose that the same geospatial statistical techniques can be applied to HIV. We used these techniques to estimate the number of HIV-infected individuals in Maseru (a health-care district in Lesotho) and establish their geographical location. The district of Maseru is a relatively large area, ab

• br A tactical change in research and advocacy is

  2019-06-27

  

  A tactical change in research and advocacy is needed urgently before mental health services will be made a priority in low-income and middle-income countries. Mental disorders and substance misuse are the greatest contributors to the global burden of disability, with 175·3 million years lost to di

• br In their policy analysis Yusra Ribhi Shawar and

  2019-06-27

  

  In their policy analysis, Yusra Ribhi Shawar and colleagues (August, 2015) outline the complex responses needed to make surgery a global health priority, highlighting as a major challenge that “consensus needs to be reached on solutions”. Professional interests might have forestalled consensus on

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