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OxLDL down regulates eNOS and up regulates iNOS
2020-01-29
OxLDL down-regulates eNOS and up-regulates iNOS, thereby augmenting the formation of NO and protein S-nitrosylation in human endothelial GKT137831 [26]. Importantly, iNOS-mediated S-nitrosylation plays an increasingly significant role in cardiovascular diseases [34]. For example, iNOS-mediated IRE1
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br Materials and methods br Discussion To date
2020-01-29
Materials and methods Discussion To date, only a fraction of studies pertaining to analysis of avian semen have focused on the study of DNA, with the vast majority being associated with the effects of cryopreservation on sperm DNA integrity (Kotłowska et al., 2007, Madeddu et al., 2009, Partyk
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br Results and discussion A systematic search for
2020-01-29
Results and discussion A systematic search for genes encoding H+-PPases was carried out by PCR using genomic DNA from a wide range of protozoa as templates and degenerate oligonucleotides, designed from amino hpdp domains conserved in H+-PPases of higher plants and the proteobacterium R. rubrum,
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We have performed our MSP
2020-01-29
We have performed our MSP analyses as real-time PCR using SybrGreen (Fig. 2). The results of the beta-actin PCR vary in each sample group because the amount of DNA for bisulfite treatment was adjusted to a constant volume of serum (500μl) rather than to equal amounts of DNA. Because we expected lowe
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Here we examine the associations between serum pro
2020-01-29
Here, we examine the associations between serum pro and anti-inflammatory cytokines and cognitive functioning in early-stage bipolar I disorder (BDI) patients. As per previous studies, ‘early-stage’ was defined as being within three years of the first manic episode (Kauer-Sant\'Anna et al., 2009). W
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br Materials and methods br Acknowledgements We thank Drs Na
2020-01-25
Materials and methods Acknowledgements We thank Drs. Nathan Sherer (University of Wisconsin-Madison) and Bryan Cullen (Duke University) for generous reagent gifts. The following reagent was obtained through the NIH AIDS Reagent Program, Division of AIDS, NIAID, NIH: HIV-2ROD phage from Dr. Ron
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Due to the results of the experiment
2020-01-25
Due to the results of the experiment we decided to deploy our cloud service infrastructure with two platform-independent servers instead of one or three. This decision was based on two factors: (a) the use of more than one server is useful to avoid a bottleneck in the system, and (b) using more than
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Apparently no study has been undertaken
2020-01-25
Apparently, no study has been undertaken on alterations in cholinesterase activity and its correlation with neurological disorders in clinical case of trypanosomosis in buffaloes. Therefore, the present study was undertaken to evaluate the alterations in cholinesterase activity in clinical cases of
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Although the analysis described above
2020-01-25
Although the analysis described above goes far to explain the mechanism of CCK-8 perturbations through CHK1 inhibition, it raises important questions about the mechanism by which WT RAS isoforms promote CHK1 S280 phosphorylation. Previous reports have shown that both the MAPK-RSK and PI3K-AKT pathwa
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pak 4 Ageing is associated with increased reactive oxygen sp
2020-01-25
Ageing is associated with increased reactive oxygen species (ROS) production, oxidative stress and oxidative damage [43,44]. Overproduction of ROS can impair endothelial function by suppressing NO synthesis and scavenging NO thereby decreasing its overall bioavailability. Moreover, sustained oxidati
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br Results br Discussion The origin and fate of
2020-01-25
Results Discussion The origin and fate of Tfh cells has been intensely studied since their first description 14 years ago (Breitfeld et al., 2000, Schaerli et al., 2000). Although mice engineered to report BCL6 (Kitano et al., 2011, Liu et al., 2012) and interleukin-21 (IL-21) (Lüthje et al.,
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nutlin mg In human neuroblastoma SH SY Y cells and in
2020-01-25
In human neuroblastoma SH-SY5Y nutlin mg and in lymphoma Jurkat cells, Yamanaka et al. [56] showed that exogenously added 24(S)-hydroxycholesterol could be efficiently esterified by ACAT1. These results suggest that both ACAT1 and ACAT2 can control the oxysterol levels by directly esterifying them,
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During the course of enzymatic
2020-01-25
During the course of enzymatic digestion, protein is digested into large peptides and these large peptides are then further digested into small fragments. αs1-Casein f15–39, which contains 25 amino salinomycin residues was the longest iTRAQ-labelled peptide identified in the samples digested with G
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Despite robust translation of GA only small
2020-01-25
Despite robust translation of GA, only small amounts of GR and GP were translated in cultured etravirine mg and chick embryo spinal cord neural cells from the 75 copies of G4C2 in monocistronic constructs. Interestingly, GA is also the most common dipeptide found in autopsy tissue in FALS patients
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GLP signaling mediates important renal
2020-01-25
GLP-1 signaling mediates important renal functions [101], as suggested by the expression of both DPP-4 and GLP-1R in the kidney of several species, including humans [102]. However, controversial data exists on the specific expression pattern of these proteins, based on the specificity and sensitivit
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