• br Material and methods br Results br

  2020-10-19

  

  Material and methods Results Discussion Monomeric CDK5 shows no enzymatic activity and requires the association with a regulatory partner for activation (Dhavan and Tsai, 2001). Here, we found that CDK7 might be one of the partners required for activation of CDK5 in the skin tissue, based o

• br Acknowledgments We thank the Lapaha Community and

  2020-10-19

  

  Acknowledgments We thank the Lapaha Community and Nobles (His Serene Highness Prince Kalaniuvalu Fotofili, Her Serene Highness Princess Marcella Taumoepeau Tupou Kalaniuvalu Fotofili and Her Royal Highness Mele Siu\'ilikutapu Kalaniuvalu Fotofili) and the Ministry of Internal Affairs (Government

• Bovine collagen type II a

  2020-10-19

  

  Bovine collagen type II, a fibrillar collagen mainly found in cartilage, comprises 24 potentially glycosylated lysine residues within its collagen domain. Detailed analysis revealed that 22 out of 23 of these lysine residues are hydroxylated and carry variable numbers of Gal(β1-O) and Glc(α1-2)Gal(β

• br Physiological roles for EPAC

  2020-10-19

  

  Physiological roles for EPAC isoforms: vascular function The effects of cAMP on limiting vascular endothelial cell (VEC) inflammation and vascular smooth muscle cell (VSMC) proliferation have been well documented 36, 37, 38. However, recent work has demonstrated that several key effects of cAMP i

• The endothelin receptor type B EDNRB belongs to the

  2020-10-19

  

  The endothelin receptor type B (EDNRB) belongs to the family of G protein-coupled receptors, which functions as a vital regulatory factor in signal transduction in cells, locating on human chromosome 13q22.3 (Ayala-Valdovinos et al., 2016; Bregar et al., 2018; Morimoto et al., 2018; Widowati et al.,

• E is a classical initiator protein and as

  2020-10-19

  

  E1 is a classical initiator protein and, as such, plays several roles in the initiation and catalysis of viral DNA synthesis. E1 must first recognize a specific segment of the viral Olomoucine known as the “origin of DNA replication”, or “ori” for short. For most PV types examined to date, the mini

• It is conceivable however that the distortion induced by ado

  2020-10-17

  

  It is conceivable, however, that the distortion induced by adozelesin in dsDNA may decrease the processivity of the translocating RecBCD enzyme so that it dissociates more frequently from adducted DNA relative to unmodified DNA. Premature termination from the DNA would also produce partially unwound

• br Application of the screening system for ITP binding

  2020-10-17

  

  Application of the screening system for ITP-binding proteins Inosine is a nucleoside with hypoxanthine as a base. Inosine nucleotides are relatively abundant in human ha tag because inosine monophosphate (IMP) is a general precursor molecule for the de novo synthesis of AMP and GMP or a product

• Since Slaughter s proposal of a genetic field

  2020-10-17

  

  Since Slaughter’s proposal of a genetic field defect concept for the explanation of the local relapse occurrence, much evidence has accumulated for its confirmation. The last ten years brought evidence that the genetic changes in the field are frequently accompanied by epigenetic aberrations. The ep

• fiin br Methods br Results The characteristics of the contro

  2020-10-17

  

  Methods Results The characteristics of the 20 control subjects and 63 patients stratified by SDB severity, matched for age, sex, and BMI z-score, are described in Table 1. As expected, AHI, OAI, ODI, and SLT90% increased and SpO2 decreased progressively with the severity of the disease. Dis

• In a recent study a CMV DNA load

  2020-10-16

  

  In a recent study, a CMV DNA load cut-off of 500 IU/ml in BAL fluid was found to have a positive predictive value of ∼50% for the presence of probable CMV pneumonia (considering a prevalence of this event of 10% among patients at risk and undergoing BAL testing). Tan et al., in contrast, found CMV D

• All tested antibodies exhibited positive immunoreactivity in

  2020-10-16

  

  All tested acetylcholine chloride exhibited positive immunoreactivity in NSCLC tumors, with N’-epitope being the less expressed (both as overall positivity and number of positive cases, or intensity combined with number of positive cells, as provided by H-Score. This result is in accordance with pr

• The intimate interactions between flavonoids and ER

  2020-10-16

  

  The intimate interactions between flavonoids and ERα have been more extensively studied than their ERβ interactions because of the dominant role of ERα in some important diseases (Ye et al., 2018) including breast cancer (more than 80% of human breast cancers are ERα positive) (Turner et al., 2015),

• br Disclaimer Statement br Introduction The erythropoietin p

  2020-10-16

  

  Disclaimer Statement Introduction The erythropoietin-producing hepatoma (Eph) receptors represent the largest class of receptor tyrosine kinases (RTKs). They are type I transmembrane proteins that interact with their membrane-bound ligands the ephrins and facilitate cell-to-cell contacts resul

• On the other hand although the cardiovascular

  2020-10-16

  

  On the other hand, although the cardiovascular effects of Epac have been investigated more intensely in recent years [31], there are hardly any studies that suggest or discard a participation of Epac in endothelium-dependent cAMP-induced relaxation. Only our previous results in rat Indoximod contra

15188 records 741/1013 page Previous Next First page 上5页 741742743744745 下5页 Last page