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Extracellular uridine can be transported across the
2021-04-16

Extracellular uridine can be transported across the cell membrane to enter the nucleotide salvage pathway. A colon cancer cell line supplemented with uridine was capable of growing normally in the presence of 1 μM brequinar (Peters et al., 1992). The supplemented uridine may be transported into the
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osi sc 175 br Discussion Electroporation is a convenient and
2021-04-16

Discussion Electroporation is a convenient and efficient way to introduce foreign material into osi sc 175 [10], [16], [17], [18]. There are a lot of different protocols for transfection with electroporation. It was reported that there are several parameters that are relevant to successful elect
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Pulmonary fibroblasts can regulate the wound healing process
2021-04-15

Pulmonary fibroblasts can regulate the wound healing process by secreting and processing extracellular matrix (ECM), chemokines, and cytokines. However, persistent and atypical fibroblast proliferation can result in ECM accumulation and may trigger the onset or development of pulmonary fibrosis [[17
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br Acknowledgements br Introduction Laryngeal cancers
2021-04-15

Acknowledgements Introduction Laryngeal cancers are the most frequent cancers of the head and neck region and their occurrence is strongly associated with the exposure to cigarette smoke and the consumption of strong alcohols. Almost all laryngeal cancers are squamous cell carcinomas. Usually
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br The role of TNFs and AD
2021-04-15

The role of TNFs and AD The TNF superfamily includes 19 members that can bind 29 different receptors [56, 57]; the 19 members are Lta, TNF-α, lymphotoxin-β (LTβ), OX40L, TNF associated activation protein (TRAP, also named CD40L or gp39), factor associated suicide ligand (FasL), CD70, CD153, 4-1BB
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Herein we report the expression of shrimp Cdk
2021-04-15

Herein we report the expression of shrimp Cdk-2 in hepatopancreas, gills and muscle, finding higher expression in hepatopancreas and gills and lower expression in muscle. No significant changes due to hypoxia and hypoxia reoxygenation were detected on the expression of Cdk-2 in hepatopancreas and gi
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br Conclusion br Conflict of interest br Acknowledgments The
2021-04-15

Conclusion Conflict of interest Acknowledgments The authors extend their appreciation to the Deanship of Scientific Research at King Saud University for funding the work through the research group project No. RGP-120. Introduction Methods Results Conclusions Introduction Pat
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Sixty eight male Sprague Dawley rats were acquired
2021-04-15

Sixty-eight male Sprague–Dawley rats were acquired from the University of South Dakota Laboratory Animal Services (Vermillion, SD, USA) and housed in pairs at 22°C (60% relative humidity) on reverse 12h light/dark they have to say (dark cycle started at 10:00a.m.) with food and water freely accessi
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GZD824 We further examined our hypothesis
2021-04-15

We further examined our hypothesis that the activation of CRF and CCK systems is responsible for the enhanced anxiety-like behavior induced by immobilization stress using two antagonists to block the expression of CRF1 and CCK2 receptors. It was found that CCK2 receptor antagonist CR2945 or CRF1 ant
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br Material and methods br Results br Discussion br
2021-04-15

Material and methods Results Discussion Conclusions To conclude, although CPT2 and CPT1 must have co-evolved to establish the carnitine shuttling, these enzymes are the most distantly related carnitine transferases, split early in evolution, during which a switch occurred in their locati
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RNA seq results also support the similarity
2021-04-15

RNA-seq results also support the similarity between ESC- and YS-derived B-1 progenitors. Bmi1 expression, known as an important gene for self-renewal ability in stem cells, was reduced in ESC-derived B cells compared with YS-derived B cells, and Bmi1 overexpression improved the engraftment of ESC-de
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In countries such as China where there is
2021-04-15

In countries such as China where there is a high commercial production of rice, the use of rice husk ash (RHA) as an alternative cementing material can become a great asset for environmental rehabilitation and address the difficult disposal issues associated with this agricultural waste [23]. RHA po
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si cid In a study performed simultaneously by another
2021-04-15

In a study performed simultaneously by another group, EWS-FLI-1 introduction into unsorted murine bone marrow-derived si cid resulted in tumors with various phenotypes including one that is consistent with that of Ewing sarcoma [68]. The tumors expressed markers associated with Ewing sarcoma and di
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Inappropriate heme metabolism has been
2021-04-15

Inappropriate heme metabolism has been linked to several neuropsychiatric disorders. In the hippocampi of Alzheimer's disease (AD) patients, for example, heme was found to binds intracellular amyloid β (Aβ), resulting in reduced heme bioavailability and its functional deficiency (Atamna and Frey, 20
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br Acknowledgments The authors acknowledge funding from the
2021-04-15

Acknowledgments The authors acknowledge funding from the National Key Research and Development Program of China (2016YFA0502900) and the National Science Foundation of China (31570188). Compartment Size Regulation Regulation of compartment size is one of the most fundamental issues in biology
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