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Epinephrine Bitartrate In another study authors found
2023-02-08
In another study, authors found that ADORA1 were present on the intrinsically photosensitive retinal ganglion Epinephrine Bitartrate (ipRGCs), and application of adenosine to rat retinas reduced light-evoked spiking of ipRGCs through suppression of a cAMP-mediated pathway (Sodhi and Hartwick, 2014)
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br Introduction Cell motility is fundamentally important in
2023-02-08
Introduction Cell motility is fundamentally important in morphogenesis, wound healing, and the immune response. One of the best-studied basic types of cell movement is lamellipodial motility [1, 2], characterized by a thin (∼0.1–0.2 μm), broad (∼10–40 μm) motile appendage containing a dynamic you
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carry on Sperm total motility and hyperactivated motility ar
2023-02-08
Sperm total motility and hyperactivated motility are mediated by PLD-dependent carry on polymerization [20]. Reduction of PIP2 synthesis inhibited actin polymerization and motility, and increasing PIP2 synthesis enhanced these activities. Furthermore, sperm demonstrating low motility contained low
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br Introduction In myasthenia gravis MG autoantibodies again
2023-02-08
Introduction In myasthenia gravis (MG), autoantibodies against the native AChR conformation cause loss of AChR at the neuromuscular junction and fatigable muscle weakness (Newsom-Davis et al., 1993). The AChR is a pentameric transmembrane protein, with two splice forms of the α-subunit, P3A− and
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cytochalasin d The scattering operators associated to are de
2023-02-08
The scattering operators associated to are defined as follows: for any and , , , there exists a unique solution to the following equation such that Then the scattering operator is defined by Here is an elliptic pseudodifferential operator of order , which is conformally covariant on the boundary.
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Compounds were profiled for their inhibitory activity agains
2023-02-08
Compounds – were profiled for their inhibitory activity against dipeptidyl peptidase-IV Activity and/or Structure Homologues (DASH) [e.g. DPP2, DPP8 and DPP9] and non-DASH [eg. post-proline cleaving enzyme (PPCE), neutral endopeptidase (NEP), aminopeptidase P (APP), aminopeptidase N (APN)] enzymes.
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br Involvement of LPA receptors
2023-02-08
Involvement of LPA receptors in cancer LPA׳s effects are mediated by at least six different G protein-coupled receptors (LPA1–6). Human gastric and ovarian cancers overexpress the mRNA encoding LPA1 and LPA2 compared to healthy tissues [6], [11], [12]. Papillary and follicular thyroid cancers exh
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Although several different membrane estrogen receptors have
2023-02-08
Although several different membrane estrogen receptors have been reported (Qiu et al., 2008; Revankar et al., 2005), a large percentage of membrane-initiated steroid hormone signaling appears to be performed by a subpopulation of the same receptors that act in the nucleus. Specifically, estrogen rec
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Autophagy and apoptosis have a very complex relationship and
2023-02-08
Autophagy and apoptosis have a very complex relationship, and the precise mechanism remains to be determined. At present, a large amount of research has confirmed that autophagy can protect the cell from apoptosis in special conditions such as nutrient deficiency or growth factors deprivation; the e
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A has been reported to decrease
2023-02-08
Aβ has been reported to decrease insulin receptors and impair insulin signaling in neurons, preventing phosphorylation of Akt and glycogen synthase kinase 3β (GSK-3β), downstream of insulin signaling, and to increase phosphorylation of tau protein causing neurofibrillary tangles (Tokutake et al., 20
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Phytoremediation technology is defined as the use of
2023-02-08
Phytoremediation technology is defined as the use of plants to remove contaminants from soils or to render them harmless, and is regarded as a cost-effective, environmental-friendly method for reclaiming soils contaminated by toxic metals (Lasat, 2002, Mahar et al., 2016, Marrugo-Negrete et al., 201
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HPK 56 br Pathophysiology of Alzheimer disease Alzheimer dis
2023-02-08
Pathophysiology of Alzheimer disease Alzheimer disease is characterized by severe neurodegeneration, neuroinflammation, and progressive loss of cognitive abilities. The diagnostic criteria for dementia released by the National Institute on Aging-Alzheimer's Association define dementia as the deve
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br Acknowledgements br Introduction Diabetic complications a
2023-02-08
Acknowledgements Introduction Diabetic complications are responsible for increased morbidity and mortality of diabetic patients. Increased flow of Mycophenolate Mofetil through the polyol pathway under conditions of hyperglycemia contributes to the development of diabetic complications. Aldose
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Interaction between AhR and ligands leads to AhR transformat
2023-02-07
Interaction between AhR and ligands leads to AhR transformation (Fig. 1), characterized by a rapid receptor nuclear translocation and the formation of AhR/Arnt complex and the release of the chaperone proteins. Following AhR transformation, the AhR/Arnt complex binds to its cognate DNA consensus seq
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br Materials and methods br Results
2023-02-07
Materials and methods Results Discussion Conclusions These studies provide important mechanistic insights to explain the long-established physiological observation that obese adipose tissue has higher rates of basal lipolysis. Increased lipolysis contributes to increased hepatic Parecoxi
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