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br We value the efforts of Akram
2019-04-23
We value the efforts of Akram Ahmad and colleagues (August, 2016) in highlighting an important issue related to the regulation of antibiotic fixed-dose combination drugs (FDCs) in India. Moreover, we agree with Ahmad and colleagues that actions taken by the Indian Government to ban irrational FDCs
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Cambiemos de hemisferio y procedamos a
2019-04-22
Cambiemos de hemisferio y procedamos adrenoceptor viajar al Cusco del siglo xvi. La doctrina o parroquia que es de interés aquí –San Cristóbal Qolqanpata– parece haber sido administrada inicialmente por unos intermediarios apostólicos que poco o nada tuvieron que ver con la orden de San Francisco. L
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El reclutamiento era una tarea
2019-04-22
El reclutamiento era una tarea permanente de los grupos guerrilleros, en el caso de las mujeres, generalmente mantenían relaciones estrechas con miembros activos de la guerrilla. Hermanos, parientes o amigos sostenían discusiones en el seno familiar sobre las condiciones de injusticia social, repres
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br Rheumatic heart disease RHD affects over million people w
2019-04-22
Rheumatic heart disease (RHD) affects over 32 million people worldwide; the vast majority of patients are in low-income and middle-income countries. It is a leading cause of premature mortality in children and young adults living in endemic regions. Patients with RHD often present in an advanced s
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igf-1 receptor WHO estimates that of people with
2019-04-22
WHO estimates that 30–50% of people with tuberculosis are untreated, in part because of underdiagnosis. Patients with undiagnosed (or diagnosed and untreated) tuberculosis are most likely to transmit infection, so strategies to reduce disease burden should focus on improving the pathway to care for
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HSP plays a crucial role
2019-04-22
HSP90 plays a crucial role as a main molecular chaperone in the regulation of proteostasis such as protein refolding under stress conditions [30]. It has been established that HSP90 binds a client protein such as Raf-1 and forms more continuous and stable functional complex [29]. On the other hand,
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br CaMKII and heart failure progression
2019-04-22
CaMKII and heart failure progression CaMKII is a multifunctional serine–threonine kinase, phosphorylating target proteins. Under resting conditions, CaMKII is inactive. A rise in intracellular Ca2+ stimulates binding of Ca2+ to calmodulin (CaM), a ubiquitous Ca2+-binding protein. The Ca2+/CaM com
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Introduction In current rehabilitation practice
2019-04-22
Introduction In current rehabilitation practice for most clinicians, restorative, supportive and palliative rehabilitation are the primarily courses of treatment for colorectal cancer (CRC) patients in Taiwan. When the end result of treatment for any patient is a fully functional recovery, restorat
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According to Weitzman classification patients had a single O
2019-04-22
According to Weitzman classification [43] 15 patients had a single ONJ lesion (4A) and 9 patients had multiple lesions (4B) or a “multifocal” lesion (Table 2). Six patients interrupted the treatment with O3 gas application for disease progression (five patients) and for fear of an experimental ther
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br Control of visceral leishmaniasis requires
2019-04-22
Control of visceral leishmaniasis requires access to low-cost, safe, and effective treatment. Amphotericin causes infusion-related fever, rigor, and nephrotoxicity, limiting its use. Ambisome—a liposomal amphotericin manufactured by Gilead—is better tolerated and is effective as a single dose. How
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We did not identify age as a major factor shaping
2019-04-22
We did not identify age as a major factor shaping continuing HCV transmission and future seroprevalence. With every blood-borne disease, these epidemiological variables depend on how frequently individuals undergo medical procedures and the risk of acquiring HCV in each case. In our study, we used d
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Seg n Patricia Fagen en su estudio
2019-04-22
Según Patricia Fagen, en su estudio clásico sobre el exilio español, “un numero sorprendente de jóvenes participaron en el Movimiento 1959 y muchos más hubieran participado si hubiesen creído que había algo significativo con lo que hubieran podido contribuir”. El espíritu de ruptura con las disputas
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El problema del populismo ocup de manera
2019-04-22
El problema del populismo ocupó de manera temprana la obra de Ernesto Laclau. Su primera obra, publicada en 1977 como Politics and ideology in marxist theory. Capitalism, fascism, populism, incluye el capítulo “Hacia una teoría del populismo”. La preocupación por el asunto no es meramente teórica si
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br Materials and methods Eculizumab levels were
2019-04-22
Materials and methods Eculizumab levels were measured at Cambridge Biomedical using a manual ELISA method in which the microtitre plates are coated with C5, then blocked. Standards, controls, and unknowns were added. After incubation and washing, mouse anti-human IgG4 horseradish peroxidase (HRP)
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WHO estimates that of people with tuberculosis
2019-04-22
WHO estimates that 30–50% of people with tuberculosis are untreated, in part because of underdiagnosis. Patients with undiagnosed (or diagnosed and untreated) tuberculosis are most likely to transmit infection, so strategies to reduce disease burden should focus on improving the pathway to care for
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