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To date over mutations in KCNQ have been found
2019-06-29
To date, over 250 mutations in KCNQ1 have been found to be linked to LQT1 [34] and new LQT1 causing mutations continue to be identified. The vast majority of KCNQ1 mutations are single nucleotide substitutions (missense) or small insertion/deletions that localize to the S1-S6 transmembrane domains [
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Los movimientos que propiciaron los cosmopolitismos de Sur
2019-06-29
Los movimientos que propiciaron los cosmopolitismos de Sur y Orígenes fueron distintos: en el primer caso, se quería innovar mediante la importación, en el segundo, se buscó importar para legitimar una apuesta poética propia. La diferencia en los sentidos de estos movimientos de selección editorial
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Y es que en Estados Unidos el
2019-06-29
Y es que, en Estados Unidos, el campo denominado Cultural Studies producía una gran cantidad de investigaciones sobre la región mediante categorías de análisis propias del llamado primer mundo. En su versión latinoamericana, los Estudios Culturales llegaron dna synthesis consolidarse en los años 199
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Treatment options for elderly AML
2019-06-29
Treatment options for elderly AML must be based on four main factors: patient\'s clinical condition, disease characteristics, patient wishes and social support. Thus, the most frail and oldest among the oldest will have the least net benefit from chemotherapy or hematopoietic transplantation, even i
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Interpretation Patient centred medical education
2019-06-29
Interpretation Patient-centred medical education can improve overall satisfaction and sustained disease-specific knowledge in patients in Uganda. Our results show that printed booklets are accepted by patients and feasible to implement in a LMIC outpatient setting. Funding Trishul Siddharthan recei
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The principal difference between BrS and ERS
2019-06-28
The principal difference between BrS and ERS is related to the region of the ventricle most affected. Epicardial mapping studies in BrS patients report accentuated J waves and fragmented and/or late potentials in the epicardial region of the RVOT [129–131], whereas in ERS only accentuated J waves, p
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br As mantenedoras e os mantidos S o as organiza
2019-06-28
As mantenedoras e os mantidos São as organizações sociais que gerenciam os hospitais, determinam as políticas internas CP-868596 serem seguidas, estipulam como devem ser os atendimentos dentro das normas contratuais e diretrizes dos sus, negociam os contratos de gestão e seus aditamentos, etc. De
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Para Rozitchner la di spora proporcionaba la posibilidad de
2019-06-28
Para Rozitchner, la diáspora proporcionaba la posibilidad de averiguar por qué los sujetos políticos de los años setenta —entre los que se incluía— produjeron una fantasía y una idealidad sobre la materialidad de las fuerzas históricas. Y también, de advertir por qué el terror fue negado y excluido
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br When many of us contemplate the role
2019-06-28
When many of us contemplate the role of agriculture in feeding 7·2 billion people, we picture large-scale, industrialised, and efficient systems that produce lots of food that is shipped around the world. Although those systems are relevant, they (±)-Bay K 8644 are only one dimension of what agri
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br Tanto en el cuerpo principal de la revista
2019-06-28
Tanto en el cuerpo principal de la revista como en la sección de análisis de libros y revistas, aparecen artículos y notas de tenor necrológico, los cuales ofrecen una suerte de homenaje póstumo Missed Opportunities personajes que generalmente habían actuado en el terreno científico, filosófico o
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The patient received multiagent chemotherapy using cyclophos
2019-06-28
The patient received multiagent chemotherapy using cyclophosphamide, daunorubicin, vincristine, predonisolone and l-asparaginase, and high dose MTX/Ara-C, as well as the single-agent administration of nelarabine, hydroxyurea and tyrosine kinase inhibitors (TKIs) (imatinib and dasatinib). The convent
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Results from the present study
2019-06-28
Results from the present study also showed improvement in timelines for measles immunisation, which is scheduled at 9 months of age, almost a gap of 6 months from the last vaccine according to EPI schedule for LMICs. Although the major focus up until now has been on reminder messages, the impact of
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Previous health emergencies have shown that it
2019-06-28
Previous health emergencies have shown that it can take time to organise global collective action and provide financing to the national and local level. In such situations, a global mechanism should offer a rapid injection of liquidity to affected countries. The World Bank\'s Pandemic Emergency Fina
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br CaMKII and heart failure progression CaMKII is a
2019-06-28
CaMKII and heart failure progression CaMKII is a multifunctional serine–threonine kinase, phosphorylating target proteins. Under resting conditions, CaMKII is inactive. A rise in intracellular Ca2+ stimulates binding of Ca2+ to calmodulin (CaM), a ubiquitous Ca2+-binding protein. The Ca2+/CaM com
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br Introduction Once metastatic breast cancer cells
2019-06-28
Introduction Once metastatic breast cancer Netilmicin Sulfate structure are in the bone marrow, they hijack signals coming from the normal bone remodelling process and promote bone degradation [1]. Bone degradation is caused by osteoclasts, which have the unique property to dissolve bone mineral
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