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br Discussion ATRA and arsenic
2019-04-25
Discussion ATRA and arsenic are both known to induce differentiation syndrome but this case was notable for its severity. Previous studies of differentiation syndrome have demonstrated that APL mtor pathway treated with ATRA secrete the chemokines CCL2 and IL-8, which in combination with chemoki
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Second the growing population which was traditionally depend
2019-04-25
Second, the growing population, which was traditionally dependent on millet, barley, and maize as staples in their diet, has developed an unsustainable appetite for rice, which puts pressure on rice production. As a result, growing numbers of dams are being constructed in rivers in the Himalayas to
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With respect to the ST elevation in
2019-04-25
With respect to the ST elevation in the precordial lead, Antzelevitch et al. demonstrated that this can be an topirimate of early repolarization or J-wave caused by transient outward current (Ito)-mediated transmural differences in the early phases of the action potential. BS is an inherited disease
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Introduction Classically increased cardiac fibrosis has been
2019-04-25
Introduction Classically, increased cardiac fibrosis has been shown to be associated with altered cardiac conduction, causing conduction slowing, block, and reentry in studies on isolated animal and diseased human cardiac tissues [1–3]. Interestingly, similar findings were also demonstrated in isol
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An ERP in the ECG has been
2019-04-25
An ERP in the ECG has been shown to be familial [187–189]. ERP and ERS have been associated with variants in 7 genes. Consistent with the findings that IK-ATP activation can generate an ERP in canine ventricular wedge preparations, variants in KCNJ8 and ABCC9, responsible for the pore- forming and A
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br Remote technologies The platforms
2019-04-24
Remote technologies The platforms available for remote monitoring of ICDs differ. Wand-based (“inductive”) systems require patient-driven downloads relayed via telephone connections to tracking facilities [4,5]. These are becoming obsolete. This is because they demand coordination with a device c
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br Discussion SIS is a morphological characteristic of
2019-04-24
Discussion SIS is a morphological characteristic of the basal interventricular septum that protrudes into the LV cavity. This cardiac malformation has generally been considered a natural part of aging without pathophysiological or clinical significance [5,6]. However, several studies demonstrated
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Estes exemplos s o iniciativas importantes
2019-04-23
Estes exemplos são iniciativas importantes para termos um esboço da relação entre RG7388 Igreja católica e a política no Brasil durante primeiras décadas do século xx. Elas denotam certo poder de resistência da instituição frente a possíveis ameaças de sua hegemonia como provedora de um estatuto mor
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The patient received multiagent chemotherapy using cyclophos
2019-04-23
The patient received multiagent chemotherapy using cyclophosphamide, daunorubicin, vincristine, predonisolone and l-asparaginase, and high dose MTX/Ara-C, as well as the single-agent administration of nelarabine, hydroxyurea and tyrosine kinase inhibitors (TKIs) (imatinib and dasatinib). The convent
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br We value the efforts of Akram
2019-04-23
We value the efforts of Akram Ahmad and colleagues (August, 2016) in highlighting an important issue related to the regulation of antibiotic fixed-dose combination drugs (FDCs) in India. Moreover, we agree with Ahmad and colleagues that actions taken by the Indian Government to ban irrational FDCs
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Cambiemos de hemisferio y procedamos a
2019-04-22
Cambiemos de hemisferio y procedamos adrenoceptor viajar al Cusco del siglo xvi. La doctrina o parroquia que es de interés aquí –San Cristóbal Qolqanpata– parece haber sido administrada inicialmente por unos intermediarios apostólicos que poco o nada tuvieron que ver con la orden de San Francisco. L
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El reclutamiento era una tarea
2019-04-22
El reclutamiento era una tarea permanente de los grupos guerrilleros, en el caso de las mujeres, generalmente mantenían relaciones estrechas con miembros activos de la guerrilla. Hermanos, parientes o amigos sostenían discusiones en el seno familiar sobre las condiciones de injusticia social, repres
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br Rheumatic heart disease RHD affects over million people w
2019-04-22
Rheumatic heart disease (RHD) affects over 32 million people worldwide; the vast majority of patients are in low-income and middle-income countries. It is a leading cause of premature mortality in children and young adults living in endemic regions. Patients with RHD often present in an advanced s
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igf-1 receptor WHO estimates that of people with
2019-04-22
WHO estimates that 30–50% of people with tuberculosis are untreated, in part because of underdiagnosis. Patients with undiagnosed (or diagnosed and untreated) tuberculosis are most likely to transmit infection, so strategies to reduce disease burden should focus on improving the pathway to care for
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HSP plays a crucial role
2019-04-22
HSP90 plays a crucial role as a main molecular chaperone in the regulation of proteostasis such as protein refolding under stress conditions [30]. It has been established that HSP90 binds a client protein such as Raf-1 and forms more continuous and stable functional complex [29]. On the other hand,
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