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  • In general we measured the skin temperatures of acupoints


    In general, we measured the Sildenafil mesylate temperatures of 135 acupoints in healthy students. The skin temperatures of these acupoints had consistency at a narrow range of 34.88–36.14°C, but had differences among them arising in part from concentricity distribution to keep whole body warmness. Skin acupoint temperatures of 12 regular meridians were showed to be symmetric and correlative to the left and the right, but the acupoint temperatures of the governor vessel were symmetric and correlative to that of the conception vessel. These findings indicate that meridian acupoint temperature is characterized by a consistently narrow range, concentricity, and symmetry in healthy people. We constructed a circle map showing acupoint temperatures to vividly demonstrate these characteristics in Fig. S2. Meridian acupoint temperature may be a sensitive and valuable indicator to evaluate meridian health and a person’s health. The clinical impact of acupoint temperature disorders warrants future investigation.
    Acknowledgments The work was supported by grants from the Program for Innovative Research Team of Guilin Medical University (PIRTGMU) and the National Natural Science Foundation of China (81270934).The funding bodies had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
    Introduction Critically ill infants who receive care in a neonatal intensive care unit (NICU) are at an increased risk of nosocomial infection due to immunological immaturity and a host of invasive diagnostic and therapeutic procedures. Prior surveillance studies have shown that the rates of nosocomial infection in NICUs range from 8.7% to 74.3%. In fact, a rate of 17.5% was reported in a tertiary hospital in Taiwan. In spite of the use of various infection control strategies such as prophylactic antibiotics, immunoglobulins, and physical barriers, the prevalence of nosocomial infections in NICUs still remains high. For several decades, there has been controversy over whether or not the inanimate environment of a NICU is associated with the risk of nosocomial infection, but there have been scant few studies on this issue. Furthermore, the Institute for Healthcare Improvement recently developed the concept of “bundles” to help health care providers more reliably deliver the best possible care for patients undergoing particular treatments with inherent risks. However, limited information is available on bundle care in neonates. Herein, we compared the nosocomial infection rates and the change of microorganisms in a tertiary NICU before and after the unit was moved to a new location. Catheter care bundle strategies were introduced to the new unit.
    Results From November 1, 2008 to October 31, 2012, data were collected from the NICU of TCVGH. A total of 512 neonates were admitted to the NICU and enrolled in monomer study, with a male/female ratio of 1 to 0.91, respectively. Two hundred and forty-two neonates were admitted to the old NICU from November 1, 2008 to October 31, 2010, and 270 neonates spent time in the new facility from November 1, 2010 to October 31, 2012 (Table 3). The mean birth body weight of neonates was 1827 g in the old NICU group and 1798 g in the new NICU group, respectively. The most common gestational age was less than 32 weeks in both groups. The average hospital stay was 27.53 days in the old Sildenafil mesylate NICU and 25.82 days in the new NICU. There were no significant differences in gender ratio, gestational age, birth body weight, and the length of hospitalization between the two groups (Table 3). There were 46 episodes of definitive nosocomial infection in the old NICU group and 30 in the new NICU group (Table 4). There was no outbreak during the study period, based on the CDC definition of nosocomial infection outbreak. The rate of nosocomial infection episodes decreased from 19.0% (46/242) to 11.1% (30/270) (P = 0.01). The average infection rate decreased from 6.26 cases per 1000 patient-days in the old NICU to 4.09 cases per 1000 patient-days in the new NICU, which was a significant decrease (P = 0.03). The most common infection site was bloodstream in both groups, which decreased from 8.3% in the old NICU to 3.7% in the new NICU (P = 0.03). The total number of the bloodstream infections, lower respiratory tract infections, and urinary tract infections declined from 13.6% (33/242) in the old NICU to 5.9% (16/270) in the new NICU (P = 0.003).