• Murine RNase Inhibitor: Transforming Viral RNA Research a...

  2025-09-27

  Discover how Murine RNase Inhibitor delivers exceptional RNA degradation prevention and oxidation resistance in advanced viral RNA assays. This article explores novel mechanistic insights and applications distinct from standard epigenetics or vaccine workflows.

• EZ Cap Cy5 Firefly Luciferase mRNA: Precision Tools for I...

  2025-09-26

  Explore the advanced capabilities of EZ Cap Cy5 Firefly Luciferase mRNA (5-moUTP) in mammalian systems, focusing on immune activation suppression and dual-mode detection for in vivo imaging. This in-depth analysis reveals novel strategies for translational research and mRNA delivery optimization.

• Cy3-UTP: Illuminating RNA Folding Pathways at Single-Nucl...

  2025-09-25

  Explore how Cy3-UTP, a leading fluorescent RNA labeling reagent, uniquely enables direct visualization of transient RNA folding intermediates and conformational dynamics. This article offers a deep dive into mechanistic insights and experimental design strategies that set it apart in RNA biology research.

• Cyclopamine as a Precision Hedgehog Pathway Tool: Beyond ...

  2025-09-24

  Discover how Cyclopamine, a potent Hedgehog signaling inhibitor, enables advanced mechanistic studies in cancer research and developmental biology. This article provides a unique systems-level analysis and explores novel experimental approaches, setting it apart from conventional reviews.

• CB-5083: Targeting p97 AAA-ATPase to Disrupt Protein Home...

  2025-09-23

  CB-5083 is a potent, selective p97 inhibitor that disrupts protein homeostasis and induces apoptosis in cancer cells. This article delves into its mechanistic action, research applications, and implications for multiple myeloma and solid tumor studies.

• In our previous study we showed that normal

  2025-03-03

  

  In our previous study we showed that normal and cancerous DNA Damage DNA Repair Library of kidney exhibit the activity of alcohol dehydrogenase and aldehyde dehydrogenase. Furthermore, the activity of class I ADH isoenzymes and total ADH were significantly higher in cancer tissue than in unchanged r

• Previous studies suggest that TGF contributes to the pathoge

  2025-03-03

  

  Previous studies suggest that TGF-β contributes to the pathogenesis of diabetic renal injury [47]. TGF-β stimulates matrix production and prevents matrix degradation, which leads to increase collagen deposition and glomerulosclerosis [48]. In the current study ABT702 significantly reduced renal coll

• Since the introduction of zebrafish into the laboratory

  2025-03-03

  

  Since the introduction of zebrafish into the laboratory, many milestones have been achieved that firmly establish this organism as a prominent genetic model for biology and medicine. Many features make this species an organism of easy maintenance in laboratory which provides advantages to understand

• br ACh and ER tests hereafter Spasm provocation tests

  2025-03-03

  

  ACh and ER tests hereafter Spasm provocation tests have self-limitations to document coronary artery spasm during daily life. In the past reports, ST elevation was reproducible in some patients with variant Benzoylmesaconitine by the administration of ACh or ER. However, we now employ the ER and

• Considering the physicochemical stability results on Fig it

  2025-03-03

  

  Considering the physicochemical stability results on Fig. 5, it was observed that the particles are stable when they are stored at 4 °C for 30 days. After day 30, a significant increase was observed in particle size, but at the end of the 90 days the SLN particle size is still below 100 nm. Stabilit

• fluc While the yeasts and see Glossary each

  2025-03-03

  

  While the yeasts and (see Glossary) each contain only one Aurora homolog, Ipl1p (increase in ploidy 1) and Ark1 (Aurora-related kinase 1), respectively 5, 6, , and Xenopus laevis contain two Aurora kinases: Aurora A and Aurora B [4]. Mammals have three Aurora kinases, A, B, and C (Figure 1). In an

• Our data indicate that the D domain only needs

  2025-03-03

  

  Our data indicate that the D1 domain only needs to hydrolyze ATP a few times, or perhaps even just once, during the processing of a given substrate molecule, whereas the D2 domain hydrolyzes ATP many times. Consistent with this model, only D2 contains the canonical aromatic pore loop residues implic

• Suspecting that ACL might regulate the

  2025-03-01

  

  Suspecting that ACL might regulate the expression or activity of myogenic transcription factors, Das knocked down MyoD and found that such intervention abolished the effect of ACL on fast MyHC expression and that, conversely, MyoD overexpression partially rescued reduced fast MyHC expression caused

• Introduction the DNA damage response important

  2025-03-01

  

  Introduction: the DNA damage response — important implications for tumour development and treatment Cells are invariably challenged by tens of thousands of lesions inflicted on their DNA everyday (Lindhal, 1993). This DNA damage can be caused exogenously by exposure to different types of radiation

• br Aromatase the key enzyme for estrogen formation in

  2025-03-01

  

  Aromatase: the key enzyme for estrogen formation in adipose tissue Estrogens are synthesized from androgens by aromatase, a member of the cytochrome P450 superfamily, which is the rate-limiting enzyme in estrogen biosynthesis (Santen et al, 2009, Simpson et al, 1994). At the cellular level, aroma

15931 records 6/1063 page Previous Next First page 上5页 678910 下5页 Last page